Gene

Iqsec3

Species
Rattus norvegicus
Symbol
Iqsec3
Name
IQ motif and Sec7 domain ArfGEF 3
Synonyms
  • IQ motif and Sec7 domain 3
  • IQ motif and SEC7 domain-containing protein 3
Biotype
protein coding gene
Automated Description
Predicted to enable guanyl-nucleotide exchange factor activity. Involved in activation of GTPase activity; postsynapse organization; and regulation of small GTPase mediated signal transduction. Is active in GABA-ergic synapse. Orthologous to human IQSEC3 (IQ motif and Sec7 domain ArfGEF 3).
RGD Description
Predicted to enable guanyl-nucleotide exchange factor activity. Involved in activation of GTPase activity; postsynapse organization; and regulation of small GTPase mediated signal transduction. Is active in GABA-ergic synapse. Orthologous to human IQSEC3 (IQ motif and Sec7 domain ArfGEF 3); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; allethrin.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10663
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
154.62M154.63M154.64M154.65M154.66M154.67M154.68M154.69M154.70M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions