Version: 8.0.0
Date: Tue Jan 28 2025
Pla2g4c
Rattus norvegicusRGD:1594658
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Pla2g4c

Species
Rattus norvegicus
Symbol
Pla2g4c
Name
phospholipase A2 group IVC
Synonyms
  • cytosolic phospholipase A2 gamma
  • LOC292645
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including calcium ion binding activity; calcium-dependent phospholipid binding activity; and phospholipase activity. Predicted to be involved in glycerophospholipid metabolic process and lipid droplet formation. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; lipid droplet; and mitochondrial membrane. Predicted to be active in cytosol; nuclear envelope; and nucleoplasm. Orthologous to human PLA2G4C (phospholipase A2 group IVC).
RGD Description
Predicted to enable several functions, including calcium ion binding activity; calcium-dependent phospholipid binding activity; and phospholipase activity. Predicted to be involved in glycerophospholipid metabolic process and lipid droplet formation. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; lipid droplet; and mitochondrial membrane. Predicted to be active in cytosol; nuclear envelope; and nucleoplasm. Orthologous to human PLA2G4C (phospholipase A2 group IVC); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 3,3',4,4',5-pentachlorobiphenyl.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10728
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Pla2g4c molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Pla2g4c role
            Pla2g4c genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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