Gene

Pacs2

Species
Rattus norvegicus
Symbol
Pacs2
Name
phosphofurin acidic cluster sorting protein 2
Synonyms
  • hypothetical protein LOC691631
  • LOC691631
Biotype
protein coding gene
Automated Description
Predicted to enable transmembrane transporter binding activity. Predicted to be involved in endoplasmic reticulum calcium ion homeostasis; mitochondrion-endoplasmic reticulum membrane tethering; and protein localization to plasma membrane. Predicted to act upstream of or within protein localization to phagophore assembly site. Predicted to be located in endoplasmic reticulum and mitochondrion. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 66. Orthologous to human PACS2 (phosphofurin acidic cluster sorting protein 2).
RGD Description
Predicted to enable transmembrane transporter binding activity. Predicted to be involved in endoplasmic reticulum calcium ion homeostasis; mitochondrion-endoplasmic reticulum membrane tethering; and protein localization to plasma membrane. Predicted to act upstream of or within protein localization to phagophore assembly site. Predicted to be located in endoplasmic reticulum and mitochondrion. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 66. Orthologous to human PACS2 (phosphofurin acidic cluster sorting protein 2); INTERACTS WITH amphetamine; endosulfan; methoxychlor.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13280
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
132.10M132.11M132.12M132.13M132.14M132.15M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions