Gene

Tsen54

Species
Rattus norvegicus
Symbol
Tsen54
Name
tRNA splicing endonuclease subunit 54
Synonyms
  • LOC690308
  • similar to tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54)
Biotype
protein coding gene
Automated Description
Predicted to be involved in tRNA-type intron splice site recognition and cleavage. Predicted to be part of tRNA-intron endonuclease complex. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2A; pontocerebellar hypoplasia type 4; and pontocerebellar hypoplasia type 5. Orthologous to human TSEN54 (tRNA splicing endonuclease subunit 54).
RGD Description
Predicted to be involved in tRNA-type intron splice site recognition and cleavage. Predicted to be part of tRNA-intron endonuclease complex. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2A; pontocerebellar hypoplasia type 4; and pontocerebellar hypoplasia type 5. Orthologous to human TSEN54 (tRNA splicing endonuclease subunit 54); PARTICIPATES IN tRNA maturation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21027
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
101.042M101.043M101.044M101.045M101.046M101.047M101.048M101.049M101.050M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions