Predicted to enable ATP binding activity; microfilament motor activity; and myosin binding activity. Involved in cardiac muscle contraction; response to ethanol; and response to xenobiotic stimulus. Predicted to be located in several cellular components, including I band; filopodium; and lamellipodium. Predicted to be part of protein-containing complex. Predicted to be active in actin filament; glutamatergic synapse; and sarcomere. Biomarker of hypertension. Human ortholog(s) of this gene implicated in atrial heart septal defect 5; dilated cardiomyopathy; dilated cardiomyopathy 1R; and hypertrophic cardiomyopathy 11. Orthologous to human ACTC1 (actin alpha cardiac muscle 1).
RGD Description
Predicted to enable ATP binding activity; microfilament motor activity; and myosin binding activity. Involved in cardiac muscle contraction; response to ethanol; and response to xenobiotic stimulus. Predicted to be located in several cellular components, including I band; filopodium; and lamellipodium. Predicted to be part of protein-containing complex. Predicted to be active in actin filament; glutamatergic synapse; and sarcomere. Biomarker of hypertension. Human ortholog(s) of this gene implicated in atrial heart septal defect 5; dilated cardiomyopathy; dilated cardiomyopathy 1R; and hypertrophic cardiomyopathy 11. Orthologous to human ACTC1 (actin alpha cardiac muscle 1); PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.