Gene

Agtr1b

Species
Rattus norvegicus
Symbol
Agtr1b
Name
angiotensin II receptor, type 1b
Synonyms
  • Agtr1
  • Angiotensin II receptor, type 1 (AT1B)
Biotype
protein coding gene
Automated Description
Predicted to enable angiotensin type I receptor activity. Involved in several processes, including angiotensin-activated signaling pathway; cellular response to dexamethasone stimulus; and positive regulation of branching involved in ureteric bud morphogenesis. Predicted to be active in plasma membrane. Biomarker of hypertension and renovascular hypertension. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; artery disease (multiple); chronic kidney disease; neurodegenerative disease (multiple); and sarcoidosis. Orthologous to human AGTR1 (angiotensin II receptor type 1).
RGD Description
Predicted to enable angiotensin type I receptor activity. Involved in several processes, including angiotensin-activated signaling pathway; cellular response to dexamethasone stimulus; and positive regulation of branching involved in ureteric bud morphogenesis. Predicted to be active in plasma membrane. Biomarker of hypertension and renovascular hypertension. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; artery disease (multiple); chronic kidney disease; neurodegenerative disease (multiple); and sarcoidosis. Orthologous to human AGTR1 (angiotensin II receptor type 1); PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; angiotensin III signaling pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10489
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
102.85M102.86M102.87M102.88M102.89M102.90M102.91M102.92M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions