Predicted to enable angiotensin type I receptor activity. Involved in several processes, including angiotensin-activated signaling pathway; cellular response to dexamethasone stimulus; and positive regulation of branching involved in ureteric bud morphogenesis. Predicted to be active in plasma membrane. Biomarker of hypertension and renovascular hypertension. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; artery disease (multiple); chronic kidney disease; neurodegenerative disease (multiple); and sarcoidosis. Orthologous to human AGTR1 (angiotensin II receptor type 1).
RGD Description
Predicted to enable angiotensin type I receptor activity. Involved in several processes, including angiotensin-activated signaling pathway; cellular response to dexamethasone stimulus; and positive regulation of branching involved in ureteric bud morphogenesis. Predicted to be active in plasma membrane. Biomarker of hypertension and renovascular hypertension. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; artery disease (multiple); chronic kidney disease; neurodegenerative disease (multiple); and sarcoidosis. Orthologous to human AGTR1 (angiotensin II receptor type 1); PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; angiotensin III signaling pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.