Gene

Akap11

Species
Rattus norvegicus
Symbol
Akap11
Name
A-kinase anchoring protein 11
Synonyms
  • A kinase (PRKA) anchor protein 11
  • A-kinase anchor protein 11
Biotype
protein coding gene
Automated Description
Enables kinase regulator activity; protein kinase A binding activity; and protein phosphatase 1 binding activity. Involved in positive regulation of establishment of endothelial barrier and positive regulation of protein phosphorylation. Located in peroxisome. Part of protein-containing complex. Orthologous to human AKAP11 (A-kinase anchoring protein 11).
RGD Description
Enables kinase regulator activity; protein kinase A binding activity; and protein phosphatase 1 binding activity. Involved in positive regulation of establishment of endothelial barrier and positive regulation of protein phosphorylation. Located in peroxisome. Part of protein-containing complex. Orthologous to human AKAP11 (A-kinase anchoring protein 11); PARTICIPATES IN protein kinase A (PKA) signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10226
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
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      Alleles and Variants

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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            mRatBN7.2
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            53.915M53.920M53.925M53.930M53.935M53.940M53.945M53.950M53.955M

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Akap11 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
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              Genetic Interactions

              Akap11 role
              Akap11 genetic perturbation
              Interactor gene
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