Gene

Arg2

Species
Rattus norvegicus
Symbol
Arg2
Name
arginase 2
Synonyms
  • AII type II arginase
  • AII, type II arginase
Biotype
protein coding gene
Automated Description
Enables arginase activity and nitric-oxide synthase binding activity. Involved in several processes, including arginine catabolic process to ornithine; cellular response to cytokine stimulus; and cellular response to dexamethasone stimulus. Located in mitochondrion. Used to study hypertension. Biomarker of acute kidney failure; end stage renal disease; hypertension; and ureteral obstruction. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ARG2 (arginase 2).
RGD Description
Enables arginase activity and nitric-oxide synthase binding activity. Involved in several processes, including arginine catabolic process to ornithine; cellular response to cytokine stimulus; and cellular response to dexamethasone stimulus. Located in mitochondrion. Used to study hypertension. Biomarker of acute kidney failure; end stage renal disease; hypertension; and ureteral obstruction. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ARG2 (arginase 2); PARTICIPATES IN urea cycle pathway; arginine and proline metabolic pathway; Entamoebiasis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43782
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
97.940M97.945M97.950M97.955M97.960M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions