Version: 8.0.0
Date: Tue Jan 28 2025
Arnt
Rattus norvegicusRGD:2153
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Arnt

Species
Rattus norvegicus
Symbol
Arnt
Name
aryl hydrocarbon receptor nuclear translocator
Synonyms
  • Arnt1
  • Aryl hydrocarbon receptor nuclear translocator 1
Biotype
protein coding gene
Automated Description
Contributes to sequence-specific DNA binding activity. Involved in several processes, including G1 to G0 transition; nitric oxide metabolic process; and response to dexamethasone. Predicted to be located in cytoplasm and nuclear body. Predicted to be part of RNA polymerase II transcription regulator complex and nuclear aryl hydrocarbon receptor complex. Predicted to be active in nucleus. Biomarker of hypertension. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human ARNT (aryl hydrocarbon receptor nuclear translocator).
RGD Description
Contributes to sequence-specific DNA binding activity. Involved in several processes, including G1 to G0 transition; nitric oxide metabolic process; and response to dexamethasone. Predicted to be located in cytoplasm and nuclear body. Predicted to be part of RNA polymerase II transcription regulator complex and nuclear aryl hydrocarbon receptor complex. Predicted to be active in nucleus. Biomarker of hypertension. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human ARNT (aryl hydrocarbon receptor nuclear translocator); PARTICIPATES IN aryl hydrocarbon receptor signaling pathway; hypoxia inducible factor pathway; renal cell carcinoma pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23042
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
    References
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Download all Alleles/Variants for all genes of the species

        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
          Source
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            Sequence Feature Viewer

            Genome location
            Assembly version
            mRatBN7.2
            Viewer Help
            183.00M183.01M183.02M183.03M183.04M183.05M

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Arnt molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              Arnt role
              Arnt genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
              Reference
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