Enables calcium ion binding activity; cytoskeletal protein binding activity; and enzyme binding activity. Contributes to calcium-dependent cysteine-type endopeptidase activity. Involved in several processes, including cellular response to interferon-beta; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of myoblast fusion. Located in several cellular components, including external side of plasma membrane; focal adhesion; and neuronal cell body. Biomarker of hypertrophic cardiomyopathy; sciatic neuropathy; and traumatic brain injury. Orthologous to human CAPN2 (calpain 2).
RGD Description
Enables calcium ion binding activity; cytoskeletal protein binding activity; and enzyme binding activity. Contributes to calcium-dependent cysteine-type endopeptidase activity. Involved in several processes, including cellular response to interferon-beta; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of myoblast fusion. Located in several cellular components, including external side of plasma membrane; focal adhesion; and neuronal cell body. Biomarker of hypertrophic cardiomyopathy; sciatic neuropathy; and traumatic brain injury. Orthologous to human CAPN2 (calpain 2); PARTICIPATES IN the proteolytic pathway involving calcium-dependent proteases; Alzheimer's disease pathway; apoptotic cell death pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.