Predicted to enable several functions, including RNA-DNA hybrid ribonuclease activity; RNA-directed DNA polymerase activity; and zinc ion binding activity. Predicted to be involved in ceramide metabolic process; intracellular sphingolipid homeostasis; and sphingolipid biosynthetic process. Predicted to act upstream of or within negative regulation of ceramide biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of serine palmitoyltransferase complex. Orthologous to human ORMDL1 (ORMDL sphingolipid biosynthesis regulator 1).
RGD Description
Predicted to enable several functions, including RNA-DNA hybrid ribonuclease activity; RNA-directed DNA polymerase activity; and zinc ion binding activity. Predicted to be involved in ceramide metabolic process; intracellular sphingolipid homeostasis; and sphingolipid biosynthetic process. Predicted to act upstream of or within negative regulation of ceramide biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of serine palmitoyltransferase complex. Orthologous to human ORMDL1 (ORMDL sphingolipid biosynthesis regulator 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; endosulfan.