Gene

Cd8a

Species
Rattus norvegicus
Symbol
Cd8a
Name
CD8 subunit alpha
Synonyms
  • CD8 antigen 32 kDa chain
  • CD8 antigen alpha-chain
Biotype
protein coding gene
Automated Description
Enables protein kinase binding activity. Involved in response to methamphetamine hydrochloride. Located in cell surface. Biomarker of amphetamine abuse and brain infarction. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human CD8A (CD8 subunit alpha).
RGD Description
Enables protein kinase binding activity. Involved in response to methamphetamine hydrochloride. Located in cell surface. Biomarker of amphetamine abuse and brain infarction. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human CD8A (CD8 subunit alpha); PARTICIPATES IN interleukin-12 signaling pathway; antigen processing and presentation pathway; primary immunodeficiency pathway; INTERACTS WITH (+)-schisandrin B; (R)-lipoic acid; 1-naphthyl isothiocyanate.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10441
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
103.3660M103.3665M103.3670M103.3675M103.3680M103.3685M103.3690M103.3695M103.3700M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions