Gene

Rad9a

Species
Rattus norvegicus
Symbol
Rad9a
Name
RAD9 checkpoint clamp component A
Synonyms
  • cell cycle checkpoint control protein RAD9A
  • LOC100361529
Biotype
protein coding gene
Automated Description
Predicted to enable 3'-5' exonuclease activity; SH3 domain binding activity; and enzyme binding activity. Predicted to be involved in DNA integrity checkpoint signaling; DNA repair; and cellular response to ionizing radiation. Predicted to act upstream of or within positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of checkpoint clamp complex. Orthologous to human RAD9A (RAD9 checkpoint clamp component A).
RGD Description
Predicted to enable 3'-5' exonuclease activity; SH3 domain binding activity; and enzyme binding activity. Predicted to be involved in DNA integrity checkpoint signaling; DNA repair; and cellular response to ionizing radiation. Predicted to act upstream of or within positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of checkpoint clamp complex. Orthologous to human RAD9A (RAD9 checkpoint clamp component A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Cuprizon; diazinon.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15237
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
201.49M201.50M201.51M201.52M201.53M201.54M201.55M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions