Predicted to enable 3'-5' exonuclease activity; SH3 domain binding activity; and enzyme binding activity. Predicted to be involved in DNA integrity checkpoint signaling; DNA repair; and cellular response to ionizing radiation. Predicted to act upstream of or within positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of checkpoint clamp complex. Orthologous to human RAD9A (RAD9 checkpoint clamp component A).
RGD Description
Predicted to enable 3'-5' exonuclease activity; SH3 domain binding activity; and enzyme binding activity. Predicted to be involved in DNA integrity checkpoint signaling; DNA repair; and cellular response to ionizing radiation. Predicted to act upstream of or within positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of checkpoint clamp complex. Orthologous to human RAD9A (RAD9 checkpoint clamp component A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Cuprizon; diazinon.