Gene

Kank2

Species
Rattus norvegicus
Symbol
Kank2
Name
KN motif and ankyrin repeat domains 2
Synonyms
  • KN motif and ankyrin repeat domain-containing protein 2
  • KN motif and ankyrin repeat domain-containing protein 2-like
Biotype
protein coding gene
Automated Description
Predicted to be involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; podocyte cell migration; and regulation of intracellular signal transduction. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in nephrotic syndrome type 16 and palmoplantar keratoderma and woolly hair. Orthologous to human KANK2 (KN motif and ankyrin repeat domains 2).
RGD Description
Predicted to be involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; podocyte cell migration; and regulation of intracellular signal transduction. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in nephrotic syndrome type 16 and palmoplantar keratoderma and woolly hair. Orthologous to human KANK2 (KN motif and ankyrin repeat domains 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24168
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
20.315M20.320M20.325M20.330M20.335M20.340M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions