Enables GMP 5'-nucleotidase activity and IMP 5'-nucleotidase activity. Involved in adenosine metabolic process and purine nucleoside monophosphate metabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II).
RGD Description
Enables GMP 5'-nucleotidase activity and IMP 5'-nucleotidase activity. Involved in adenosine metabolic process and purine nucleoside monophosphate metabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; cadmium dichloride.