Gene

Mir224

Species
Rattus norvegicus
Symbol
Mir224
Name
microRNA 224
Synonyms
  • rno-mir-224
Biotype
ncRNA gene
Automated Description
Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in miRNA-mediated post-transcriptional gene silencing and negative regulation of cell migration. Predicted to act upstream of or within several processes, including Wnt signaling pathway; cellular response to leukemia inhibitory factor; and cellular response to lipopolysaccharide. Biomarker of hepatocellular carcinoma and steatotic liver disease. Orthologous to human MIR224 (microRNA 224).
RGD Description
Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in miRNA-mediated post-transcriptional gene silencing and negative regulation of cell migration. Predicted to act upstream of or within several processes, including Wnt signaling pathway; cellular response to leukemia inhibitory factor; and cellular response to lipopolysaccharide. Biomarker of hepatocellular carcinoma and steatotic liver disease. Orthologous to human MIR224 (microRNA 224); INTERACTS WITH 2,5-hexanedione; amiodarone; dexamethasone.
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
150.06509M150.06510M150.06511M150.06512M150.06513M150.06514M150.06515M150.06516M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions