Species

Rattus norvegicus

Symbol

Cel

Name

carboxyl ester lipase

Synonyms

Bal
bile salt-activated lipase

Biotype

protein coding gene

Automated Description

Enables carboxylic ester hydrolase activity and glycosphingolipid binding activity. Predicted to be involved in ceramide catabolic process; intestinal cholesterol absorption; and pancreatic juice secretion. Located in extracellular space and zymogen granule. Part of protein-containing complex. Human ortholog(s) of this gene implicated in lipomatosis; maturity-onset diabetes of the young type 8; type 1 diabetes mellitus; and type 2 diabetes mellitus. Orthologous to human CEL (carboxyl ester lipase).

RGD Description

Enables glycosphingolipid binding activity; lipase activity; and retinyl-palmitate esterase activity. Predicted to be involved in ceramide catabolic process; intestinal cholesterol absorption; and pancreatic juice secretion. Located in extracellular space and zymogen granule. Part of protein-containing complex. Human ortholog(s) of this gene implicated in lipomatosis; maturity-onset diabetes of the young type 8; type 1 diabetes mellitus; and type 2 diabetes mellitus. Orthologous to human CEL (carboxyl ester lipase); PARTICIPATES IN glycerolipid metabolic pathway; steroid biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-ethoxyethanol; 2-methoxyethanol.

Cross References

Additional Information

Literature

Orthology

Gene tree: PANTHER:PTHR43903

Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse

Paralogy

Function - GO Annotations

Show functions with at least one experimental evidence

Pathways

No data available

Phenotypes

Primary Sources: None
Other Sources: None

Phenotype Term	Annotation details	References
No records match query. Try removing filters.

Showing 0 - 0 of 0 rows

per page

Disease Associations

Include negative annotationsCases where the expected disease association was NOT found

Cell color indicative of annotation volume

Alleles and Variants

Allele/Variant Symbol	Allele Synonyms	Category	Variant	Variant type	Molecular consequence	Has Disease Annotations	Has Phenotype Annotations
No records match query. Try removing filters.

Showing 0 - 0 of 0 rows

per page

Download all Alleles/Variants for all genes of the species

Transgenic Alleles

Species (carrying the transgene)	Allele symbol	Transgenic construct	Expressed components	Knock-down targets	Regulatory regions	Has Disease Annotations	Has Phenotype Annotations
No records match query. Try removing filters.

Showing 0 - 0 of 0 rows

per page

Models

Model name	Experimental condition	Associated Human Diseases	Associated Phenotypes	Modifier	Source
No records match query. Try removing filters.

Showing 0 - 0 of 0 rows

per page

Sequence Feature Viewer

Genome location

Chr3:11883532...11891035 - (7.50 kb)

Assembly version

mRatBN7.2

Viewer Help

Data currently unavailable; sequence viewer under construction

Sequence Details

Loading...

Expression

Primary Sources

None

Other Sources

Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Cel molecule type	Interactor gene	Interactor species	Interactor molecule type	Detection method	Source	Reference
No records match query. Try removing filters.

Showing 0 - 0 of 0 rows

per page

Genetic Interactions

Cel role	Cel genetic perturbation	Interactor gene	Interactor species	Interactor role	Interactor genetic perturbation	Interaction type	Phenotype or trait	Source	Reference
No records match query. Try removing filters.

Showing 0 - 0 of 0 rows

per page