Version: 8.0.0Date: Tue Jan 28 2025
Gene
Cryaa
- Species
- Rattus norvegicus
- Symbol
- Cryaa
- Name
- crystallin, alpha A
- Synonyms
- Acry-1
- alpha-crystallin A chain
- Biotype
- protein coding gene
- Automated Description
- Enables identical protein binding activity. Involved in several processes, including lens development in camera-type eye; response to hydrogen peroxide; and response to lead ion. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and nucleus. Used to study cataract. Biomarker of cataract; galactosemia; and ocular hypertension. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Orthologous to human CRYAA (crystallin alpha A).
- RGD Description
- Enables identical protein binding activity. Involved in several processes, including lens development in camera-type eye; response to hydrogen peroxide; and response to lead ion. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and nucleus. Used to study cataract. Biomarker of cataract; galactosemia; and ocular hypertension. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Orthologous to human CRYAA (crystallin alpha A); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (R)-lipoic acid; (R,R,R)-alpha-tocopherol; 5-azacytidine.
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR45640
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Sequence Feature Viewer
- Genome location
- Chr20:9783605...9787351 + (3.75 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction