Gene

Cycs

Species
Rattus norvegicus
Symbol
Cycs
Name
cytochrome c, somatic
Synonyms
  • CYCSA
  • Cytochrome C expressed in somatic tissues
Biotype
protein coding gene
Automated Description
Enables enzyme binding activity. Involved in several processes, including mitochondrial electron transport, cytochrome c to oxygen; negative regulation of hydrogen peroxide biosynthetic process; and response to ischemia. Located in cytosol. Human ortholog(s) of this gene implicated in cholangiocarcinoma; lung non-small cell carcinoma; pancreatic cancer; and thrombocytopenia. Orthologous to human CYCS (cytochrome c, somatic).
RGD Description
Enables enzyme binding activity. Involved in several processes, including mitochondrial electron transport, cytochrome c to oxygen; negative regulation of hydrogen peroxide biosynthetic process; and response to ischemia. Located in cytosol. Human ortholog(s) of this gene implicated in cholangiocarcinoma; lung non-small cell carcinoma; pancreatic cancer; and thrombocytopenia. Orthologous to human CYCS (cytochrome c, somatic); PARTICIPATES IN intrinsic apoptotic pathway; cardiolipin metabolic pathway; ceramide signaling pathway; INTERACTS WITH (+)-taxifolin; (-)-epigallocatechin 3-gallate; (R)-adrenaline.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11961
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
60.2830M60.2832M60.2834M60.2836M60.2838M60.2840M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions