gamma-aminobutyric acid type A receptor subunit beta1
Synonyms
GABA(A) receptor subunit beta-1
GABAAR subunit beta-1
Biotype
protein coding gene
Automated Description
Enables GABA receptor binding activity; GABA-A receptor activity; and monoatomic ion channel activity. Involved in several processes, including cellular response to histamine; central nervous system neuron development; and response to progesterone. Located in dendrite; nuclear envelope; and plasma membrane. Part of GABA-A receptor complex. Is active in GABA-ergic synapse; postsynaptic specialization membrane; and presynaptic active zone membrane. Biomarker of hepatic encephalopathy. Human ortholog(s) of this gene implicated in autistic disorder and developmental and epileptic encephalopathy 45. Orthologous to human GABRB1 (gamma-aminobutyric acid type A receptor subunit beta1).
RGD Description
Enables GABA receptor binding activity; GABA-A receptor activity; and monoatomic ion channel activity. Involved in several processes, including cellular response to histamine; central nervous system neuron development; and response to progesterone. Located in dendrite; nuclear envelope; and plasma membrane. Part of GABA-A receptor complex. Is active in GABA-ergic synapse; postsynaptic specialization membrane; and presynaptic active zone membrane. Biomarker of hepatic encephalopathy. Human ortholog(s) of this gene implicated in autistic disorder and developmental and epileptic encephalopathy 45. Orthologous to human GABRB1 (gamma-aminobutyric acid type A receptor subunit beta1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.