Enables adenylate cyclase inhibiting G protein-coupled glutamate receptor activity. Involved in adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway and chemical synaptic transmission. Predicted to be located in Golgi membrane; endoplasmic reticulum membrane; and new growing cell tip. Predicted to be active in cell tip; dendrite; and plasma membrane. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1B. Orthologous to human GRM6 (glutamate metabotropic receptor 6).
RGD Description
Enables adenylate cyclase inhibiting G protein-coupled glutamate receptor activity. Involved in adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway and chemical synaptic transmission. Predicted to be located in Golgi membrane; endoplasmic reticulum membrane; and new growing cell tip. Predicted to be active in cell tip; dendrite; and plasma membrane. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1B. Orthologous to human GRM6 (glutamate metabotropic receptor 6); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; ammonium acetate.