Gene

Igfbp5

Species
Rattus norvegicus
Symbol
Igfbp5
Name
insulin-like growth factor binding protein 5
Synonyms
  • IBP-5
  • IGF-binding protein 5
Biotype
protein coding gene
Automated Description
Enables insulin-like growth factor binding activity. Involved in intracellular signal transduction and response to organic cyclic compound. Predicted to be located in cytoplasm and nucleus. Predicted to be part of insulin-like growth factor ternary complex. Predicted to be active in extracellular space. Biomarker of congenital diaphragmatic hernia. Orthologous to human IGFBP5 (insulin like growth factor binding protein 5).
RGD Description
Enables insulin-like growth factor binding activity. Involved in intracellular signal transduction and response to organic cyclic compound. Predicted to be located in cytoplasm and nucleus. Predicted to be part of insulin-like growth factor ternary complex. Predicted to be active in extracellular space. Biomarker of congenital diaphragmatic hernia. Orthologous to human IGFBP5 (insulin like growth factor binding protein 5); PARTICIPATES IN insulin-like growth factor signaling pathway; INTERACTS WITH (R,R,R)-alpha-tocopherol; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,10-phenanthroline.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11551
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
74.450M74.452M74.454M74.456M74.458M74.460M74.462M74.464M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions