Version: 8.0.0
Date: Tue Jan 28 2025
Jtb
Rattus norvegicusRGD:2942
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Jtb

Species
Rattus norvegicus
Symbol
Jtb
Name
jumping translocation breakpoint
Synonyms
  • LOC100365813
  • MGC72461
Biotype
protein coding gene
Automated Description
Predicted to enable protein kinase binding activity. Predicted to be involved in mitotic cytokinesis; positive regulation of protein kinase activity; and regulation of cell population proliferation. Predicted to act upstream of or within apoptotic mitochondrial changes. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm and midbody. Predicted to colocalize with centrosome and spindle. Orthologous to human JTB (jumping translocation breakpoint).
RGD Description
Predicted to enable protein kinase binding activity. Predicted to be involved in mitotic cytokinesis; positive regulation of protein kinase activity; and regulation of cell population proliferation. Predicted to act upstream of or within apoptotic mitochondrial changes. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm and midbody. Predicted to colocalize with centrosome and spindle. Orthologous to human JTB (jumping translocation breakpoint); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13041
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Jtb molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Jtb role
            Jtb genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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