Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; nuclear receptor binding activity; and transcription coactivator activity. Involved in several processes, including cellular response to hypoxia; positive regulation of macrophage activation; and positive regulation of peroxisome proliferator activated receptor signaling pathway. Part of protein-DNA complex. Is active in nucleus. Biomarker of crescentic glomerulonephritis and renal carcinoma. Orthologous to human JUND (JunD proto-oncogene, AP-1 transcription factor subunit).
RGD Description
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; nuclear receptor binding activity; and transcription coactivator activity. Involved in several processes, including cellular response to hypoxia; positive regulation of macrophage activation; and positive regulation of peroxisome proliferator activated receptor signaling pathway. Part of protein-DNA complex. Is active in nucleus. Biomarker of crescentic glomerulonephritis and renal carcinoma. Orthologous to human JUND (JunD proto-oncogene, AP-1 transcription factor subunit); PARTICIPATES IN platelet-derived growth factor signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (S)-amphetamine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.