Gene

Jund

Species
Rattus norvegicus
Symbol
Jund
Name
JunD proto-oncogene, AP-1 transcription factor subunit
Synonyms
  • jun D proto-oncogene
  • JunD-FL isoform
Biotype
protein coding gene
Automated Description
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; nuclear receptor binding activity; and transcription coactivator activity. Involved in several processes, including cellular response to hypoxia; positive regulation of macrophage activation; and positive regulation of peroxisome proliferator activated receptor signaling pathway. Part of protein-DNA complex. Is active in nucleus. Biomarker of crescentic glomerulonephritis and renal carcinoma. Orthologous to human JUND (JunD proto-oncogene, AP-1 transcription factor subunit).
RGD Description
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; nuclear receptor binding activity; and transcription coactivator activity. Involved in several processes, including cellular response to hypoxia; positive regulation of macrophage activation; and positive regulation of peroxisome proliferator activated receptor signaling pathway. Part of protein-DNA complex. Is active in nucleus. Biomarker of crescentic glomerulonephritis and renal carcinoma. Orthologous to human JUND (JunD proto-oncogene, AP-1 transcription factor subunit); PARTICIPATES IN platelet-derived growth factor signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (S)-amphetamine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11462
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
18.7342M18.7344M18.7346M18.7348M18.7350M18.7352M18.7354M18.7356M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions