A structural constituent of myelin sheath. Involved in several processes, including negative regulation of axonogenesis; response to progesterone; and response to tumor necrosis factor. Located in cell surface and compact myelin. Used to study demyelinating disease. Biomarker of Huntington's disease; brain disease (multiple); diabetic neuropathy; hypothyroidism; and schizophrenia. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human MBP (myelin basic protein).
RGD Description
A structural constituent of myelin sheath. Involved in several processes, including negative regulation of axonogenesis; response to progesterone; and response to tumor necrosis factor. Located in cell surface and compact myelin. Used to study demyelinating disease. Biomarker of Huntington's disease; brain disease (multiple); diabetic neuropathy; hypothyroidism; and schizophrenia. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human MBP (myelin basic protein); INTERACTS WITH (20S)-20-hydroxypregn-4-en-3-one; (S)-nicotine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine.