Gene

Mc3r

Species
Rattus norvegicus
Symbol
Mc3r
Name
melanocortin 3 receptor
Synonyms
  • MC3-R
  • melanocortin receptor 3
Biotype
protein coding gene
Automated Description
Enables melanocortin receptor activity and peptide hormone binding activity. Involved in several processes, including adenylate cyclase-modulating G protein-coupled receptor signaling pathway; homoiothermy; and sodium ion homeostasis. Predicted to be active in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in obesity. Orthologous to human MC3R (melanocortin 3 receptor).
RGD Description
Enables melanocortin receptor activity and peptide hormone binding activity. Involved in several processes, including adenylate cyclase-modulating G protein-coupled receptor signaling pathway; homoiothermy; and sodium ion homeostasis. Predicted to be active in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in obesity. Orthologous to human MC3R (melanocortin 3 receptor); PARTICIPATES IN melanocortin system pathway; G protein mediated signaling pathway via Galphas family; INTERACTS WITH ammonium chloride; bisphenol A; C60 fullerene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22750
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
161.0164M161.0165M161.0166M161.0167M161.0168M161.0169M161.0170M161.0171M161.0172M161.0173M161.0174M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions