Enables serotonin binding activity. Involved in several processes, including cellular response to serotonin; hepatic stellate cell activation; and inositol phosphate metabolic process. Located in dendrite; neuronal cell body; and plasma membrane. Used to study heart valve disease. Biomarker of brain infarction and congestive heart failure. Human ortholog(s) of this gene implicated in metabolic dysfunction-associated steatohepatitis and steatotic liver disease. Orthologous to human HTR2B (5-hydroxytryptamine receptor 2B).
RGD Description
Enables serotonin binding activity. Involved in several processes, including cellular response to serotonin; hepatic stellate cell activation; and inositol phosphate metabolic process. Located in dendrite; neuronal cell body; and plasma membrane. Used to study heart valve disease. Biomarker of brain infarction and congestive heart failure. Human ortholog(s) of this gene implicated in metabolic dysfunction-associated steatohepatitis and steatotic liver disease. Orthologous to human HTR2B (5-hydroxytryptamine receptor 2B); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (R)-noradrenaline; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.