Gene

Ptma

Species
Rattus norvegicus
Symbol
Ptma
Name
prothymosin alpha
Synonyms
  • alpha-prothymosin
  • prothymosin-alpha
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor binding activity; histone binding activity; and histone chaperone activity. Involved in positive regulation of NF-kappaB transcription factor activity and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human PTMA (prothymosin alpha).
RGD Description
Predicted to enable DNA-binding transcription factor binding activity; histone binding activity; and histone chaperone activity. Involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of NF-kappaB transcription factor activity; and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human PTMA (prothymosin alpha); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22745
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
87.1765M87.1770M87.1775M87.1780M87.1785M87.1790M87.1795M87.1800M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions