Gene

Gabra6

Species
Rattus norvegicus
Symbol
Gabra6
Name
gamma-aminobutyric acid type A receptor subunit alpha6
Synonyms
  • GABA-A receptor alpha-6 subunit
  • GABA(A) receptor subunit alpha-6
Biotype
protein coding gene
Automated Description
Enables diazepam binding activity; heterocyclic compound binding activity; and inhibitory extracellular ligand-gated monoatomic ion channel activity. Contributes to GABA-A receptor activity; GABA-gated chloride ion channel activity; and benzodiazepine receptor activity. Involved in GABAergic synaptic transmission and response to ethanol. Located in dendrite; neuronal cell body membrane; and synaptic membrane. Part of receptor complex. Is active in several cellular components, including cerebellar Golgi cell to granule cell synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic specialization membrane. Used to study obesity. Orthologous to human GABRA6 (gamma-aminobutyric acid type A receptor subunit alpha6).
RGD Description
Enables diazepam binding activity; heterocyclic compound binding activity; and inhibitory extracellular ligand-gated monoatomic ion channel activity. Contributes to GABA-A receptor activity; GABA-gated chloride ion channel activity; and benzodiazepine receptor activity. Involved in GABAergic synaptic transmission and response to ethanol. Located in dendrite; neuronal cell body membrane; and synaptic membrane. Part of receptor complex. Is active in several cellular components, including cerebellar Golgi cell to granule cell synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic specialization membrane. Used to study obesity. Orthologous to human GABRA6 (gamma-aminobutyric acid type A receptor subunit alpha6); INTERACTS WITH (S)-nicotine; ammonium chloride; Ampullosporin.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18945
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
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26.812M26.814M26.816M26.818M26.820M26.822M26.824M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions