Gene

Lbp

Species
Rattus norvegicus
Symbol
Lbp
Name
lipopolysaccharide binding protein
Synonyms
  • BPI fold containing family D, member 2
  • Bpifd2
Biotype
protein coding gene
Automated Description
Enables lipopolysaccharide binding activity. Involved in several processes, including positive regulation of macrophage activation; positive regulation of phagocytosis, engulfment; and response to ethanol. Located in extracellular space. Used to study obesity. Biomarker of liver cirrhosis; metabolic dysfunction and alcohol associated liver disease; obstructive jaundice; and periodontitis. Orthologous to human LBP (lipopolysaccharide binding protein).
RGD Description
Enables lipopolysaccharide binding activity. Involved in several processes, including positive regulation of macrophage activation; positive regulation of phagocytosis, engulfment; and response to ethanol. Located in extracellular space. Used to study obesity. Biomarker of liver cirrhosis; obstructive jaundice; and periodontitis. Orthologous to human LBP (lipopolysaccharide binding protein); PARTICIPATES IN interleukin-6 signaling pathway; Toll-like receptor signaling pathway; tuberculosis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10504
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
146.955M146.960M146.965M146.970M146.975M146.980M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions