Gene

Ramp2

Species
Rattus norvegicus
Symbol
Ramp2
Name
receptor activity modifying protein 2
Synonyms
  • receptor (calcitonin) activity modifying protein 2
  • receptor (G protein-coupled) activity modifying protein 2
Biotype
protein coding gene
Automated Description
Enables coreceptor activity. Involved in several processes, including receptor internalization; response to estradiol; and response to progesterone. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of adrenomedullin receptor complex. Predicted to be active in cell surface. Biomarker of adult respiratory distress syndrome; congestive heart failure; hypertension; kidney disease; and pulmonary hypertension. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human RAMP2 (receptor activity modifying protein 2).
RGD Description
Enables coreceptor activity. Involved in several processes, including receptor internalization; response to estradiol; and response to progesterone. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of adrenomedullin receptor complex. Predicted to be active in cell surface. Biomarker of adult respiratory distress syndrome; congestive heart failure; hypertension; kidney disease; and pulmonary hypertension. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human RAMP2 (receptor activity modifying protein 2); INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14076
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
86.190M86.195M86.200M86.205M86.210M86.215M86.220M86.225M86.230M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions