Version: 8.0.0
Date: Tue Jan 28 2025
Slc6a6
Rattus norvegicusRGD:61912
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Slc6a6

Species
Rattus norvegicus
Symbol
Slc6a6
Name
solute carrier family 6 member 6
Synonyms
  • sodium- and chloride-dependent taurine transporter
  • Solute carrier 6 ,member 6 (taurine transporter)
Biotype
protein coding gene
Automated Description
Enables gamma-aminobutyric acid:sodium:chloride symporter activity; taurine binding activity; and taurine:sodium symporter activity. Involved in gamma-aminobutyric acid import; import across plasma membrane; and taurine transmembrane transport. Located in dendrite; neuronal cell body; and plasma membrane. Part of plasma membrane protein complex. Orthologous to human SLC6A6 (solute carrier family 6 member 6).
RGD Description
Enables gamma-aminobutyric acid:sodium:chloride symporter activity; taurine binding activity; and taurine:sodium symporter activity. Involved in gamma-aminobutyric acid import; import across plasma membrane; and taurine transmembrane transport. Located in dendrite; neuronal cell body; and plasma membrane. Part of plasma membrane protein complex. Orthologous to human SLC6A6 (solute carrier family 6 member 6); INTERACTS WITH 1-benzylpiperazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11616
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Slc6a6 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Slc6a6 role
            Slc6a6 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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