Gene

Gpr37

Species
Rattus norvegicus
Symbol
Gpr37
Name
G protein-coupled receptor 37
Synonyms
  • Ednrbl
  • G protein-coupled receptor 37 (endothelin receptor type B-like)
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including G protein-coupled receptor activity; Hsp70 protein binding activity; and PDZ domain binding activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; cellular response to reactive oxygen species; and dendrite development. Predicted to act upstream of or within dopamine biosynthetic process; locomotion involved in locomotory behavior; and positive regulation of dopamine metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be part of receptor complex and ubiquitin ligase complex. Predicted to be active in cell surface; plasma membrane; and synapse. Orthologous to human GPR37 (G protein-coupled receptor 37).
RGD Description
Predicted to enable several functions, including G protein-coupled receptor activity; Hsp70 protein binding activity; and PDZ domain binding activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; cellular response to reactive oxygen species; and dendrite development. Predicted to act upstream of or within dopamine biosynthetic process; locomotion involved in locomotory behavior; and positive regulation of dopamine metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be part of receptor complex and ubiquitin ligase complex. Predicted to be active in cell surface; plasma membrane; and synapse. Orthologous to human GPR37 (G protein-coupled receptor 37); PARTICIPATES IN Parkinson's disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46216
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
54.140M54.142M54.144M54.146M54.148M54.150M54.152M54.154M54.156M54.158M54.160M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions