Gene

Nme7

Species
Rattus norvegicus
Symbol
Nme7
Name
NME/NM23 family member 7
Synonyms
  • 3'-5' exonuclease NME7
  • NDK 7
Biotype
protein coding gene
Automated Description
Predicted to enable 3'-5' exonuclease activity and protein kinase activity. Predicted to be involved in flagellated sperm motility and regulation of microtubule nucleation. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; epithelial cilium movement involved in extracellular fluid movement; and intraciliary transport. Predicted to be located in ciliary basal body; cytoplasm; and nucleus. Predicted to be part of gamma-tubulin ring complex. Predicted to be active in axonemal A tubule inner sheath; centrosome; and sperm flagellum. Orthologous to human NME7 (NME/NM23 family member 7).
RGD Description
Predicted to enable 3'-5' exonuclease activity and protein kinase activity. Predicted to be involved in flagellated sperm motility and regulation of microtubule nucleation. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; epithelial cilium movement involved in extracellular fluid movement; and intraciliary transport. Predicted to be located in ciliary basal body; cytoplasm; and nucleus. Predicted to be part of gamma-tubulin ring complex. Predicted to be active in axonemal A tubule inner sheath; centrosome; and sperm flagellum. Orthologous to human NME7 (NME/NM23 family member 7); PARTICIPATES IN purine metabolic pathway; pyrimidine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43109
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
76.66M76.68M76.70M76.72M76.74M76.76M76.78M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions