Enables endopeptidase activity and enzyme binding activity. Involved in proteolysis involved in protein catabolic process. Located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; conjunctivitis; hereditary angioedema; myocardial infarction; and plasminogen deficiency type I. Orthologous to several human genes including PLG (plasminogen).
RGD Description
Enables endopeptidase activity and enzyme binding activity. Involved in proteolysis involved in protein catabolic process. Located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; conjunctivitis; hereditary angioedema; myocardial infarction; and plasminogen deficiency type I. Orthologous to several human genes including PLG (plasminogen); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.