Gene

Rin1

Species
Rattus norvegicus
Symbol
Rin1
Name
Ras and Rab interactor 1
Synonyms
  • LOC108348044
  • ras inhibitor
Biotype
protein coding gene
Automated Description
Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in endocytosis and signal transduction. Predicted to act upstream of or within associative learning; memory; and negative regulation of synaptic plasticity. Predicted to be located in several cellular components, including dendrite; neuronal cell body; and plasma membrane. Predicted to be active in cytosol and endocytic vesicle. Orthologous to human RIN1 (Ras and Rab interactor 1).
RGD Description
Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in endocytosis and signal transduction. Predicted to act upstream of or within associative learning; memory; and negative regulation of synaptic plasticity. Predicted to be located in several cellular components, including dendrite; neuronal cell body; and plasma membrane. Predicted to be active in cytosol and endocytic vesicle. Orthologous to human RIN1 (Ras and Rab interactor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23101
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
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    Variant type
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Rin1 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection method
          Source
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            Genetic Interactions

            Rin1 role
            Rin1 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
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