Gene

Tgfbi

Species
Rattus norvegicus
Symbol
Tgfbi
Name
transforming growth factor, beta induced
Synonyms
  • Big-h3
  • BIGH3
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including collagen binding activity; extracellular matrix binding activity; and identical protein binding activity. Involved in chondrocyte differentiation. Located in basement membrane. Biomarker of kidney disease. Human ortholog(s) of this gene implicated in corneal dystrophy (multiple). Orthologous to human TGFBI (transforming growth factor beta induced).
RGD Description
Predicted to enable several functions, including collagen binding activity; extracellular matrix binding activity; and identical protein binding activity. Involved in chondrocyte differentiation. Located in basement membrane. Biomarker of kidney disease. Human ortholog(s) of this gene implicated in corneal dystrophy (multiple). Orthologous to human TGFBI (transforming growth factor beta induced); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10900
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
7.960M7.965M7.970M7.975M7.980M7.985M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions