Gene

Insl3

Species
Rattus norvegicus
Symbol
Insl3
Name
insulin-like 3
Synonyms
  • ley-I-L
  • Leydig insulin-like peptide
Biotype
protein coding gene
Automated Description
Predicted to enable G protein-coupled receptor binding activity and protease binding activity. Involved in several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; oocyte maturation; and positive regulation of cAMP/PKA signal transduction. Located in extracellular space and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in cryptorchidism. Orthologous to human INSL3 (insulin like 3).
RGD Description
Predicted to enable G protein-coupled receptor binding activity and protease binding activity. Involved in several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; oocyte maturation; and positive regulation of cAMP/PKA signal transduction. Located in extracellular space and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in cryptorchidism. Orthologous to human INSL3 (insulin like 3); INTERACTS WITH (+)-taxifolin; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10423
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
18.386M18.388M18.390M18.392M18.394M18.396M18.398M18.400M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions