Predicted to enable several functions, including ABC-type transporter activity; glutathione transmembrane transporter activity; and prostaglandin transmembrane transporter activity. Involved in several processes, including positive regulation of smooth muscle cell proliferation; response to tetrachloromethane; and response to xenobiotic stimulus. Located in basolateral plasma membrane and external side of apical plasma membrane. Biomarker of cholestasis and extrahepatic cholestasis. Orthologous to human ABCC4 (ATP binding cassette subfamily C member 4 (PEL blood group)).
RGD Description
Predicted to enable several functions, including ABC-type transporter activity; glutathione transmembrane transporter activity; and prostaglandin transmembrane transporter activity. Involved in several processes, including positive regulation of smooth muscle cell proliferation; response to tetrachloromethane; and response to xenobiotic stimulus. Located in basolateral plasma membrane and external side of apical plasma membrane. Biomarker of cholestasis and extrahepatic cholestasis. Orthologous to human ABCC4 (ATP binding cassette subfamily C member 4 (PEL blood group)); PARTICIPATES IN azathioprine pharmacodynamics pathway; lamivudine pharmacokinetics pathway; mercaptopurine pharmacodynamics pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.