Gene

Slc25a5

Species
Rattus norvegicus
Symbol
Slc25a5
Name
solute carrier family 25 member 5
Synonyms
  • Adenine nucleotid translocator 2 fibroblast isoform (ATP-ADP carrier protein)
  • Adenine nucleotid translocator 2, fibroblast isoform (ATP-ADP carrier protein)
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including ATP:ADP antiporter activity; oxidative phosphorylation uncoupler activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including hemopoiesis; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; and nucleotide transmembrane transport. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Located in membrane raft and mitochondrial inner membrane. Orthologous to human SLC25A5 (solute carrier family 25 member 5).
RGD Description
Predicted to enable several functions, including ATP:ADP antiporter activity; oxidative phosphorylation uncoupler activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including hemopoiesis; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; and nucleotide transmembrane transport. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Located in membrane raft and mitochondrial inner membrane. Orthologous to human SLC25A5 (solute carrier family 25 member 5); PARTICIPATES IN calcium/calcium-mediated signaling pathway; Huntington's disease pathway; Parkinson's disease pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45635
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
116.0320M116.0325M116.0330M116.0335M116.0340M116.0345M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions