Species

Rattus norvegicus

Symbol

Cabp1

Name

calcium binding protein 1

Synonyms

calcium-binding protein 1
caldendrin

Biotype

protein coding gene

Automated Description

Enables several functions, including nuclear localization sequence binding activity; transmembrane transporter binding activity; and type 3 metabotropic glutamate receptor binding activity. Involved in negative regulation of cell communication by electrical coupling; negative regulation of transport; and postsynapse to nucleus signaling pathway. Located in several cellular components, including neuronal cell body; postsynaptic density; and subplasmalemmal coating. Part of protein-containing complex. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Biomarker of temporal lobe epilepsy. Orthologous to human CABP1 (calcium binding protein 1).

RGD Description

Enables several functions, including nuclear localization sequence binding activity; transmembrane transporter binding activity; and type 3 metabotropic glutamate receptor binding activity. Involved in negative regulation of cell communication by electrical coupling; negative regulation of transport; and postsynapse to nucleus signaling pathway. Located in several cellular components, including neuronal cell body; postsynaptic density; and subplasmalemmal coating. Part of protein-containing complex. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Biomarker of temporal lobe epilepsy. Orthologous to human CABP1 (calcium binding protein 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.

Cross References

Additional Information

Literature

Orthology

Gene tree: PANTHER:PTHR45917

Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse

Paralogy

Function - GO Annotations

Show functions with at least one experimental evidence

Pathways

No data available

Phenotypes

Primary Sources: None
Other Sources: None

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Disease Associations

Include negative annotationsCases where the expected disease association was NOT found

Cell color indicative of annotation volume

Alleles and Variants

Allele/Variant Symbol	Allele Synonyms	Category	Variant	Variant type	Molecular consequence	Has Disease Annotations	Has Phenotype Annotations
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Transgenic Alleles

Species (carrying the transgene)	Allele symbol	Transgenic construct	Expressed components	Knock-down targets	Regulatory regions	Has Disease Annotations	Has Phenotype Annotations
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Models

Model name	Experimental condition	Associated Human Diseases	Associated Phenotypes	Modifier	Source
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Sequence Feature Viewer

Genome location

Chr12:41378897...41448930 + (70.03 kb)

Assembly version

mRatBN7.2

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Data currently unavailable; sequence viewer under construction

Sequence Details

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Expression

Primary Sources

None

Other Sources

Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Cabp1 molecule type	Interactor gene	Interactor species	Interactor molecule type	Detection method	Source	Reference
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Genetic Interactions

Cabp1 role	Cabp1 genetic perturbation	Interactor gene	Interactor species	Interactor role	Interactor genetic perturbation	Interaction type	Phenotype or trait	Source	Reference
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