Enables sodium:proton antiporter activity. Involved in proton transmembrane transport and sodium ion transmembrane transport. Predicted to be located in several cellular components, including focal adhesion; neuron spine; and recycling endosome membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in end stage renal disease. Orthologous to human SLC9A5 (solute carrier family 9 member A5).
RGD Description
Enables sodium:proton antiporter activity. Involved in proton transmembrane transport and sodium ion transmembrane transport. Predicted to be located in several cellular components, including focal adhesion; neuron spine; and recycling endosome membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in end stage renal disease. Orthologous to human SLC9A5 (solute carrier family 9 member A5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.