Species

Rattus norvegicus

Symbol

Rps6ka1

Name

ribosomal protein S6 kinase A1

Synonyms

90 kDa ribosomal protein S6 kinase 1
MAP kinase-activated protein kinase 1a

Biotype

protein coding gene

Automated Description

Predicted to enable DNA-binding transcription factor binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and protein kinase activity. Involved in positive regulation of DNA-templated transcription and protein phosphorylation. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human RPS6KA1 (ribosomal protein S6 kinase A1).

RGD Description

Predicted to enable DNA-binding transcription factor binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and protein kinase activity. Involved in positive regulation of DNA-templated transcription and protein phosphorylation. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human RPS6KA1 (ribosomal protein S6 kinase A1); PARTICIPATES IN adenosine signaling pathway; fibroblast growth factor signaling pathway; mTOR signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.

Cross References

Additional Information

Literature

Orthology

Gene tree: PANTHER:PTHR24351

No data available

Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources: None
Other Sources: None

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Disease Associations

Cell color indicative of annotation volume

Gene	Association	Disease Qualifier	Disease	Evidence	Source	Based On	References
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Alleles and Variants

Allele/Variant Symbol	Allele Synonyms	Category	Variant	Variant type	Molecular consequence	Has Disease Annotations	Has Phenotype Annotations
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Download all Alleles/Variants for all genes of the species

Transgenic Alleles

Species (carrying the transgene)	Allele symbol	Transgenic construct	Expressed components	Knock-down targets	Regulatory regions	Has Disease Annotations	Has Phenotype Annotations
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Models

Model name	Experimental condition	Associated Human Diseases	Associated Phenotypes	Modifier	Source
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Sequence Feature Viewer

Genome location

Chr5:146079018...146118272 - (39.25 kb)

Assembly version

mRatBN7.2

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Sequence Details

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Expression

Primary Sources

None

Other Sources

Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Rps6ka1 molecule type	Interactor gene	Interactor species	Interactor molecule type	Detection methods	Source	Reference
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Genetic Interactions

Rps6ka1 role	Rps6ka1 genetic perturbation	Interactor gene	Interactor species	Interactor role	Interactor genetic perturbation	Interaction type	Phenotype or trait	Source	Reference
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