Gene

Aatf

Species
Rattus norvegicus
Symbol
Aatf
Name
apoptosis antagonizing transcription factor
Synonyms
  • apoptosis-antagonizing transcription factor
  • Ded
Biotype
protein coding gene
Automated Description
Enables leucine zipper domain binding activity; protein kinase binding activity; and tau protein binding activity. Involved in negative regulation of apoptotic process and positive regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of small-subunit processome and transcription regulator complex. Predicted to be active in nucleolus. Orthologous to human AATF (apoptosis antagonizing transcription factor).
RGD Description
Enables leucine zipper domain binding activity; protein kinase binding activity; and tau protein binding activity. Involved in negative regulation of apoptotic process and positive regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of small-subunit processome and transcription regulator complex. Predicted to be active in nucleolus. Orthologous to human AATF (apoptosis antagonizing transcription factor); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15565
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
69.30M69.31M69.32M69.33M69.34M69.35M69.36M69.37M69.38M69.39M

Sequence Details

Transcript: Mode:

Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

6 interactor genes based on 11 annotations
Aatf molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
Bloc1s2Rattus norvegicus
protein
  • two hybrid
PMID:17552904
protein
Bloc1s2Rattus norvegicus
protein
  • pull down
PMID:17552904
protein
Bloc1s2Rattus norvegicus
protein
  • affinity chromatography technology
PMID:17552904
protein
Dapk3Rattus norvegicus
protein
  • pull down
PMID:10580117
protein
Dapk3Rattus norvegicus
protein
  • two hybrid
PMID:10580117
protein
Dapk3Rattus norvegicus
protein
  • two hybrid
PMID:10602480
protein
MaptRattus norvegicus
protein
  • affinity chromatography technology
PMID:14697667
protein
MaptRattus norvegicus
protein
  • affinity chromatography technology
PMID:14697667
protein
Mns1Rattus norvegicus
protein
  • two hybrid
PMID:17552904
protein
Pmf1Rattus norvegicus
protein
  • two hybrid
PMID:17552904
Showing 1 - 10 of 11 rows
per page

Genetic Interactions