Gene

Napa

Species
Rattus norvegicus
Symbol
Napa
Name
NSF attachment protein alpha
Synonyms
  • alpha-SNAP
  • alpha-soluble NSF attachment protein
Biotype
protein coding gene
Automated Description
Enables syntaxin binding activity. Involved in positive regulation of ATP-dependent activity and protein-containing complex disassembly. Located in terminal bouton. Part of synaptobrevin 2-SNAP-25-syntaxin-1a complex. Is active in neuromuscular junction; postsynapse; and presynaptic active zone membrane. Orthologous to human NAPA (NSF attachment protein alpha).
RGD Description
Enables syntaxin binding activity. Involved in positive regulation of ATP-dependent activity and protein-containing complex disassembly. Located in terminal bouton. Part of synaptobrevin 2-SNAP-25-syntaxin-1a complex. Is active in neuromuscular junction; postsynapse; and presynaptic active zone membrane. Orthologous to human NAPA (NSF attachment protein alpha); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione; 4,4'-sulfonyldiphenol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13768
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
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    Variant type
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Napa molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
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            Genetic Interactions

            Napa role
            Napa genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
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