Enables 1-phosphatidylinositol-3-kinase activity. Involved in phosphatidylinositol phosphate biosynthetic process. Located in brush border membrane. Part of phosphatidylinositol 3-kinase complex. Used to study thrombosis. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in glioblastoma; prostate adenocarcinoma; prostate cancer; and type 2 diabetes mellitus. Orthologous to human PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta).
RGD Description
Enables 1-phosphatidylinositol-3-kinase activity. Involved in phosphatidylinositol phosphate biosynthetic process. Located in brush border membrane. Part of phosphatidylinositol 3-kinase complex. Used to study thrombosis. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in glioblastoma; prostate adenocarcinoma; prostate cancer; and type 2 diabetes mellitus. Orthologous to human PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; FasL mediated signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; allethrin.