Gene

Plcb2

Species
Rattus norvegicus
Symbol
Plcb2
Name
phospholipase C, beta 2
Synonyms
  • 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  • 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2
Biotype
protein coding gene
Automated Description
Enables G-protein beta/gamma-subunit complex binding activity; phosphatidylinositol phospholipase C activity; and phospholipid binding activity. Involved in detection of chemical stimulus involved in sensory perception of bitter taste and phospholipase C-activating G protein-coupled receptor signaling pathway. Part of G-protein beta/gamma-subunit complex. Orthologous to human PLCB2 (phospholipase C beta 2).
RGD Description
Enables G-protein beta/gamma-subunit complex binding activity; phosphatidylinositol phospholipase C activity; and phospholipid binding activity. Involved in detection of chemical stimulus involved in sensory perception of bitter taste and phospholipase C-activating G protein-coupled receptor signaling pathway. Part of G-protein beta/gamma-subunit complex. Orthologous to human PLCB2 (phospholipase C beta 2); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; G protein mediated signaling pathway via Galphaq family; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10336
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
105.684M105.686M105.688M105.690M105.692M105.694M105.696M105.698M105.700M105.702M105.704M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions