Gene

Plrg1

Species
Rattus norvegicus
Symbol
Plrg1
Name
pleiotropic regulator 1
Synonyms
  • MGC105439
  • pleiotropic regulator 1 homolog
Biotype
protein coding gene
Automated Description
Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within positive regulation of G1/S transition of mitotic cell cycle and protein localization to nucleus. Predicted to be located in fibrillar center; nuclear membrane; and nuclear speck. Predicted to be part of DNA replication factor A complex; Prp19 complex; and U2-type catalytic step 2 spliceosome. Orthologous to human PLRG1 (pleiotropic regulator 1).
RGD Description
Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within positive regulation of G1/S transition of mitotic cell cycle and protein localization to nucleus. Predicted to be located in fibrillar center; nuclear membrane; and nuclear speck. Predicted to be part of DNA replication factor A complex; Prp19 complex; and U2-type catalytic step 2 spliceosome. Orthologous to human PLRG1 (pleiotropic regulator 1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; ammonium chloride.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19923
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
168.410M168.412M168.414M168.416M168.418M168.420M168.422M168.424M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions