Gene

G3bp1

Species
Rattus norvegicus
Symbol
G3bp1
Name
G3BP stress granule assembly factor 1
Synonyms
  • G3bp
  • GTPase activating protein (SH3 domain) binding protein 1
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including helicase activity; molecular condensate scaffold activity; and ribosomal small subunit binding activity. Predicted to be involved in several processes, including positive regulation of stress granule assembly; positive regulation of type I interferon production; and stress granule assembly. Predicted to act upstream of or within negative regulation of canonical Wnt signaling pathway. Predicted to be located in cytoplasm. Predicted to be active in cytoplasmic stress granule and cytosol. Orthologous to human G3BP1 (G3BP stress granule assembly factor 1).
RGD Description
Predicted to enable several functions, including helicase activity; molecular condensate scaffold activity; and ribosomal small subunit binding activity. Predicted to be involved in several processes, including positive regulation of stress granule assembly; positive regulation of type I interferon production; and stress granule assembly. Predicted to act upstream of or within negative regulation of canonical Wnt signaling pathway. Predicted to be located in cytoplasm. Predicted to be active in cytoplasmic stress granule and cytosol. Orthologous to human G3BP1 (G3BP stress granule assembly factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10693
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
39.590M39.595M39.600M39.605M39.610M39.615M39.620M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions