Gene

Megf8

Species
Rattus norvegicus
Symbol
Megf8
Name
multiple EGF-like-domains 8
Synonyms
  • EGF-like domain-containing protein 4
  • EGF-like protein 4
Biotype
protein coding gene
Automated Description
Predicted to enable calcium ion binding activity. Predicted to be involved in several processes, including axon development; embryonic morphogenesis; and left/right pattern formation. Predicted to act upstream of or within several processes, including blood vessel development; embryonic brain development; and embryonic digit morphogenesis. Predicted to be located in nucleus. Predicted to be part of ubiquitin ligase complex. Predicted to be active in basement membrane. Human ortholog(s) of this gene implicated in Carpenter syndrome. Orthologous to human MEGF8 (multiple EGF like domains 8).
RGD Description
Predicted to be an extracellular matrix structural constituent. Predicted to be involved in several processes, including axon development; embryonic morphogenesis; and left/right pattern formation. Predicted to act upstream of or within several processes, including blood vessel development; embryonic brain development; and embryonic digit morphogenesis. Predicted to be located in nucleus. Predicted to be part of ubiquitin ligase complex. Predicted to be active in basement membrane. Human ortholog(s) of this gene implicated in Carpenter syndrome. Orthologous to human MEGF8 (multiple EGF like domains 8); INTERACTS WITH amitrole; ammonium chloride; beta-naphthoflavone.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46093
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
80.905M80.910M80.915M80.920M80.925M80.930M80.935M80.940M80.945M80.950M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions